Since fludrocortisone acetate is a potent mineralocorticoid, most adverse reactions to florinef are caused by this activity and include hypertension, oedema, cardiac enlargement, congestive heart failure, potassium loss and hypokalaemic alkalosis.

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Aspirin should be used cautiously in conjunction with corticosteroids in patients with hypoprothrombinaemia.

Other adverse reactions that may occur following the administration of a corticosteroid are necrotizing angiitis.thrombophlebitis.aggravation or masking of infections.insomnia.syncopal episodes.and anaphylactoid reactions.

Fludrocortisone may also be used for other purposes not listed in this medication guide.

Infants born of mothers who have received substantial doses of fludrocortisone acetate during pregnancy should be carefully observed for signs of hypoadrenalism.

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the clinical name for florinef is fludrocortisone acetate.