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Get emergency medical help if you have any of these signs of an allergic reaction. hives. difficulty breathing. swelling of your face.lips.tongue.or throat.

Patients should be informed regarding the potential benefits and risks attendant to the use of COPEGUS. Instructions on appropriate use should be given.including review of the contents of the enclosed MEDICATION GUIDE .which is not a disclosure of all or possible adverse effects.

Renal function should be evaluated in all patients prior to initiation of Copegus by estimating the patient’s creatinine clearance.

A pharmacokinetic study in 42 subjects demonstrated there is no clinically significant difference in ribavirin pharmacokinetics among Black (n=14).Hispanic (n=13) and Caucasian (n=15) subjects.

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