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Losartan is an oral medication that belongs to a class of drugs called cozaar 25 mg generic receptor blockers (ARBs). Other ARBs include irbesartan (Avapro).valsartan (Diovan).and candesartan (Atacand). Angiotensin formed cozaar 25 mg generic the blood by the action of angiotensin converting enzyme (ACE) is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells of blood vessels. Angiotensin’s attachment to the receptors causes the muscle cells to contract and the blood vessels to narrow (vasoconstrict) cozaar 25 mg generic leads to an increase in blood pressure (hypertension). Losartan (more specifically.the chemical formed when the liver converts the inactive losartan into its active form) blocks the angiotensin receptor. By blocking the action of angiotensin.losartan relaxes muscle cells and dilates blood vessels thereby reducing blood pressure.
Hydrochlorothiazide should not be used for essential hypertension in pregnant women except in rare situations where no other treatment could be used.
B. May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
Do not use if you are pregnant. If you become pregnant.stop taking this medicine and tell your doctor right away. Cozaar can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
In addition to the active metabolite.inactive metabolites are formed.including two major metabolites formed by hydroxylation of the butyl side chain and a minor metabolite.an N-2 tetrazole glucuronide.
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