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Elevated systolic or diastolic pressure causes increased cardiovascular risk.and the absolute risk increase per mmHg is greater at higher blood that even modest reductions of severe hypertension can provide substantial benefit. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example.patients with diabetes or hyperlipidemia).and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal.

Combining doxazosin with any drug that lowers your blood pressure can increase your risk for lowering your blood pressure too much. Examples of drugs that lower your blood pressure are.

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