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HPA axis suppression.Cushing syndrome.linear growth retardation.delayed weight gain.and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include low plasma cortisol levels and an absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles.headaches.and bilateral papilledema.

Clobetasol propionate was nonmutagenic in 3 different test systems. the Ames test.the Saccharomyces cerevisiae gene conversion assay.and the E. coli B WP2 fluctuation test.

Get emergency medical help if you have any of these signs of an allergic reaction. hives. difficulty breathing. swelling of your face.lips.tongue.or throat.

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